- Helicase – It unwound a portion of the DNA double helix
- DNA polymerase delta – It binds to one strand of the DNA and begins moving along that strand in the 3′ to 5′ direction, using it as a template for assembling a leading strand
- DNA polymerase epsilon – It binds to the other template strand as the double helix opens. This synthesizes discontinuous segments of polynucleotides i.e. called Okazaki fragments.
- Exonuclease (DNA polymerase I) – It finds and removes the RNA Primers
- RNA primase – It makes attachment of RNA primers to the replicating strands.
- DNA ligase – It adds phosphate in the gaps remained in the phosphate – sugar backbone
- Nucleases – It removes wrong nucleotides from the daughter strand
To know about DNA replication Steps – Process visit the page. It explains complete process of DNA replication.